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ACTH 11-24

CAS No. 4237-93-8

ACTH 11-24 ( Adrenocorticotropic Hormone (11-24) )

产品货号. M29947 CAS No. 4237-93-8

ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥806 有现货
10MG ¥1102 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    ACTH 11-24
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.
  • 产品描述
    ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.(In Vitro):ACTH (11-24) acts as an antagonist of adrenocorticotropic hormone receptor. ACTH (11-24) induces cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. The maximal cortisol release by ACTH (11-24) is enhanced by forskolin but inhibited by calcium channel blockers.(In Vivo):ACTH (11-24) blocks electroacupuncture (EA) anti-edema but not EA anti-hyperalgesia in rats.
  • 体外实验
    ACTH (11-24) elicits cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells.
  • 体内实验
    ACTH (11-24) has slight influences on circulating plasma corticosterone values and on fighting behavior.
  • 同义词
    Adrenocorticotropic Hormone (11-24)
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Adrenocorticotropic hormone receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    4237-93-8
  • 分子量
    1652.04
  • 分子式
    C77H134N24O16
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?H2O : 100 mg/mL (60.53 mM)
  • SMILES
    ——
  • 化学全称
    Sequence:Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Li ZG, et al. Adrenocorticotropin(1-10) and -(11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125(2):592-6.
产品手册
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