ACTH 11-24 ( Adrenocorticotropic Hormone (11-24) )

产品货号. M29947 CAS No. 4237-93-8

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产品名称

ACTH 11-24
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.
产品描述

ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.(In Vitro):ACTH (11-24) acts as an antagonist of adrenocorticotropic hormone receptor. ACTH (11-24) induces cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. The maximal cortisol release by ACTH (11-24) is enhanced by forskolin but inhibited by calcium channel blockers.(In Vivo):ACTH (11-24) blocks electroacupuncture (EA) anti-edema but not EA anti-hyperalgesia in rats.
同义词

Adrenocorticotropic Hormone (11-24)
通路

Others
靶点

Other Targets
受体

Adrenocorticotropic hormone receptor
研究领域

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适应症

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Li ZG, et al. Adrenocorticotropin(1-10) and -(11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125(2):592-6.

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